1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
N-Methylcoclaurine
CAS: 1472-62-4
Molecular Formula: C18H21NO3
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol - Names and Identifiers
| Name | N-Methylcoclaurine |
| Synonyms | N-Methylcoclaurine 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol |
| CAS | 1472-62-4 |
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol - Physico-chemical Properties
| Molecular Formula | C18H21NO3 |
| Molar Mass | 299.36 |
| Appearance | Powder |
| Storage Condition | 2-8℃ |
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol - Reference
| Reference Show more | 1. [IF=4.35] Xiaoji Cao et al."Green Extraction-Assisted Pseudo-Targeted Profile of Alkaloids in Lotus Seed Epicarp Based on UPLC-QTOF MS with IDA."Foods. 2022 Jan;11(7):1056 |
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol - Introduction
N-Methylcoclaurine is a natural product with the chemical formula C11H13NO and a molecular weight of 175.23g/mol. It is mainly found in the Hengzhou quercetin (Stephaniae tetrandrae).
N-Methylcoclaurine is a white crystalline solid, soluble in acid, alcohol and ether, insoluble in water. It has a bitter and slightly sweet taste. The compounds have relatively high melting and boiling points and are thermally stable.
N-Methylcoclaurine has a variety of pharmacological activities, including anti-inflammatory, antibacterial, antioxidant, anti-cancer, etc. It is widely used in traditional Chinese medicine preparations, especially for the treatment of rheumatoid arthritis, asthma and hypertension. In addition, N-Methylcoclaurine are also used for research and development of new drugs.
The preparation method of N-Methylcoclaurine is generally from the Hengzhou extraction. First, the Hengzhou umeiyuan was crushed and boiled, and then extracted and separated. The obtained extract undergoes acid-base adjustment, solvent concentration and crystallization purification, and finally a pure N-Methylcoclaurine is obtained.
N-Methylcoclaurine in general is considered to be relatively safe, but still need to pay attention to some safety matters. It may cause irritation to the respiratory system and skin, so care should be taken to avoid inhalation and contact when using it. As with any chemical, proper storage and handling is also important. When using and handling N-Methylcoclaurine, follow relevant safety practices and use appropriate personal protective equipment.
N-Methylcoclaurine is a white crystalline solid, soluble in acid, alcohol and ether, insoluble in water. It has a bitter and slightly sweet taste. The compounds have relatively high melting and boiling points and are thermally stable.
N-Methylcoclaurine has a variety of pharmacological activities, including anti-inflammatory, antibacterial, antioxidant, anti-cancer, etc. It is widely used in traditional Chinese medicine preparations, especially for the treatment of rheumatoid arthritis, asthma and hypertension. In addition, N-Methylcoclaurine are also used for research and development of new drugs.
The preparation method of N-Methylcoclaurine is generally from the Hengzhou extraction. First, the Hengzhou umeiyuan was crushed and boiled, and then extracted and separated. The obtained extract undergoes acid-base adjustment, solvent concentration and crystallization purification, and finally a pure N-Methylcoclaurine is obtained.
N-Methylcoclaurine in general is considered to be relatively safe, but still need to pay attention to some safety matters. It may cause irritation to the respiratory system and skin, so care should be taken to avoid inhalation and contact when using it. As with any chemical, proper storage and handling is also important. When using and handling N-Methylcoclaurine, follow relevant safety practices and use appropriate personal protective equipment.
Last Update：2024-04-10 22:29:15
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Product Name: N-Methylcoclaurine Visit Supplier Webpage Request for quotationCAS: 1472-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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